Tumor Cell Metabolism Imaging

Molecular imaging of tumor metabolism has obtained considerable interest, since preclinical studies have indicated a close relationship between the activation of various oncogenes and alterations of cellular metabolism. Furthermore, several clinical trials have shown that metabolic imaging can significantly impact patient management by improving tumor staging, restaging, radiation treatment planning, and monitoring of tumor response to therapy. In this topic includes recent data on the molecular mechanisms underlying the increased metabolic activity of cancer cells and discuss imaging techniques for studies of tumor glucose, lipid, and amino acid metabolism.

  • Glucose metabolism
  • Amino acid metabolism
  • Optical imaging
  • Lipid metabolism
  • PET
  • Transcriptional and epigenetic control of mitochondrial function
  • Transcriptional and epigenetic control of mitochondrial function

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