Translational Immunometabolism

The field of immunometabolism has flourished over the last decade, revealing not only the major roles played by immune cells in metabolic homeostasis but also the impact of metabolic pathways on immune cell function. As new discoveries continue to reveal the intricate links between immunology and metabolism, a key question arises: will our accumulated knowledge on immunometabolic deregulations translate into novel therapies for human diseases? In this topic will focus how local and systemic metabolism are integrated at the cellular level to regulate immune cell function and will focus on how novel insights into immunometabolism can be utilised to advance and/or bolster therapeutic interventions in metabolic diseases, inflammation, autoimmunity, and cancer.

  • Infection and host metabolic adaptation
  • Chronic inflammation and metabolic disease
  • Metabolic disruptions of immune cells
  • Cancer Immunity
  • Nutrient sensing and microbiome-host interactions
  • Regulation of gene expression and metabolism by nuclear hormone receptors
  • Respiratory mucociliary transport and innate immunity
  • Extra-oral taste receptors

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