Metabolic disease Therapies

Convenient metabolic regulation is essential for good health and well-being. The body is challenged on a daily basis with environmental and behavioral stresses that require adjustments in the type and quantity of fuels that oxidized for energy. When this ability to reciprocate to metabolic stress becomes impaired, it can lead to a number of diseases and disorders that are generally referred to as metabolic disease. Metabolic diseases affect a large proportion of the US population and have a substantial impact on the mortality rate and quality of life for afflicted individuals. Hence, many researchers are pursuing a better understanding of the underlying factors that lead to the development of metabolic diseases, the consequences of metabolic dysregulation, and the therapeutic strategies that can effectively counter the causes and consequences of this dysregulation.

  • Metabolic precision medicine
  • Diabetes
  • Obesity
  • Translating therapeutics for metabolic diseases
  • Integrated energy metabolism
  • Energy homeostasis
  • Retinal iron trafficking and its role in retinal disease
  •  Nuclear receptor signaling in the developing and diseased heart
  •  mechanism of obesity-associated insulin resistance and diabetes
  •  circadian regulation of metabolism
  • TDP-43 and amyloid beta precursor proteins (APPs) in health and disease

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